Pulse Arterial Tone (PAT) measurement


Medical device for noninvasive endothelial function assessment

EndoPAT has been extensively reviewed in scientific publications. It is based on noninvasive Peripheral Arterial Tone (PAT) signal technology described below. It measures endothelium-mediated changes in vascular tone using unique bio-sensors placed on the fingertips. These changes in arterial tone are elicited by creating a down-stream hyperemic response induced by a standard 5-minute occlusion of the brachial artery.

Measurements from the contra-lateral arm are used to control for concurrent non-endothelial dependent changes in vascular tone. The automatically calculated result is an index of endothelial function.


Equipement/ Material:

EndoPAT 2000, Itamar medical



  • Noninvasive Ventilation in Mild obesity hypoventilation syndrome: A randomized controlled trial. Borel JC, Tamisier R, Gonzalez-Bermejo J, Baguet JP, Monneret D, Arnol N, Roux-Lombard P, Wuyam B, Levy P, Pepin JL.Chest. 2011 Sep 1.
  • A critical review of peripheral arterial tone and pulse transit time as indirect diagnostic methods for detecting sleep disordered breathing and characterizing sleep structure. Pépin JL, Tamisier R, Borel JC, Baguet JP, Lévy P. Curr Opin Pulm Med. 2009 Aug 29.
  • Endothelial dysfunction and specific inflammation in obesity hypoventilation syndrome. Borel JC, Roux-Lombard P, Tamisier R, Arnaud C, Monneret D, Arnol N, Baguet JP, Levy P, Pepin JL. PLoS One. 2009 Aug 24;4(8):e6733.